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福岛核事故后中国广东核电集团核电厂抗震设计和评估进展

毛庆,吴应喜,张健,孟阿军,张涛,杨春菊,刘芳

《中国工程科学》 2013年第15卷第4期页码 46-51

摘要：

本文介绍了核电站抗震设计要求、在建和运行核电站的抗震设计情况以及运行核电站遭遇地震灾害的情况，简述了福岛核事故后世界各国核电站在抗震方面采取的措施，针对中国广东核电集团在福岛核事故后的行动进行了详细介绍，并提出了新建核电厂在抗震设计和评估方面的策略，以期通过技术手段持续提升核电站的抗震能力。

关键词：抗震设计基准超设计基准地震抗震裕量分析（SMA）隔震

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Core designing of a new type of TVS-2M FAs: neutronics and thermal-hydraulics design basis limits

Saeed GHAEMI, Farshad FAGHIHI

《能源前沿（英文）》 2021年第15卷第1期页码 256-278 doi: 10.1007/s11708-018-0583-x

摘要： One of the most important aims of this study is to improve the core of the current VVER reactors to achieve more burn-up (or more cycle length) and more intrinsic safety. It is an independent study on the Russian new proposed FAs, called TVS-2M, which would be applied for the future advanced VVERs. Some important aspects of neutronics as well as thermal hydraulics investigations (and analysis) of the new type of Fas are conducted, and results are compared with the standards PWR CDBL. The TVS-2M FA contains gadolinium-oxide which is mixed with UO (for different Gd densities and U-235 enrichments which are given herein), but the core does not contain BARs. The new type TVS-2M Fas are modeled by the SARCS software package to find the PMAXS format for three states of CZP and HZP as well as HFP, and then the whole core is simulated by the PARCS code to investigate transient conditions. In addition, the WIMS-D5 code is suggested for steady core modeling including TVS-2M FAs and/or TVS FAs. Many neutronics aspects such as the first cycle length (first cycle burn up in terms of MW d/kgU), the critical concentration of boric acid at the BOC as well as the cycle length, the axial, and radial power peaking factors, differential and integral worthy of the most reactive CPS-CRs, reactivity coefficients of the fuel, moderator, boric acid, and the under-moderation estimation of the core are conducted and benchmarked with the PWR CDBL. Specifically, the burn-up calculations indicate that the 45.6 d increase of the first cycle length (which corresponds to 1.18 MW d/kgU increase of burn-up) is the best improving aim of the new FA type called TVS-2M. Moreover, thermal-hydraulics core design criteria such as MDNBR (based on W3 correlation) and the maximum of fuel and clad temperatures (radially and axially), are investigated, and discussed based on the CDBL.

关键词： TVS-2M FAs core design basis limits VVER-1000 analysis mixture of uranium-gadolinium oxides fuels thermal-hydraulics PARCS WIMS-D5

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Seismic performance of steel MRF building with nonlinear viscous dampers

Baiping DONG,James M. RICLES,Richard SAUSE

《结构与土木工程前沿（英文）》 2016年第10卷第3期页码 254-271 doi: 10.1007/s11709-016-0348-8

摘要： This paper presents an experimental study of the seismic response of a 0.6-scale three-story seismic-resistant building structure consisting of a moment resisting frame (MRF) with reduced beam sections (RBS), and a frame with nonlinear viscous dampers and associated bracing (called the DBF). The emphasis is on assessing the seismic performance for the design basis earthquake (DBE) and maximum considered earthquake (MCE). Three MRF designs were studied, with the MRF designed for 100%, 75%, and 60%, respectively, of the required base shear design strength determined according to ASCE 7-10. The DBF with nonlinear viscous dampers was designed to control the lateral drift demands. Earthquake simulations using ensembles of DBE and MCE ground motions were conducted using the real-time hybrid simulation method. The results show the drift demand and damage that occurs in the MRF under seismic loading. Overall, the results show that a high level of seismic performance can be achieved under DBE and MCE ground motions, even for a building structure designed for as little as 60% of the base shear design strength required by ASCE 7-10 for a structure without dampers.

关键词： seismic response steel MRF nonlinear viscous damper design basis earthquake real-time hybrid simulation

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水库大坝的安全问题和已建大坝的抗震安全性

Martin Wieland

《工程（英文）》 2016年第2卷第3期页码 325-331 doi: 10.1016/J.ENG.2016.03.011

摘要：

对任何蓄水大坝工程的基本性能要求都是安全性，它包括以下安全要素：①结构安全性；②大坝安全监控；③运行安全和维护；④应急计划。长期安全包括：首先，分析影响项目的所有灾害，即自然环境灾害、人造环境灾害、特定项目和特定场地灾害。本文讨论的是大坝地震安全的特点。大坝是自20 世纪30 年代以来最早开始进行系统性抗震结构设计的建筑物，但由于多数大坝设计采用的是现今认为已过时的地震设计标准和动态分析方法，因此无法了解那些老坝的地震安全性。因此，需要基于当前最新做法，重新评估已建坝的地震安全性，并改造有缺陷的大坝。通常建议对大坝进行特定场地的地震危险性分析。当前的大坝以及用于控制强震后水库安全的设施必须能承受安全评估地震的地面运动。地震动参数可以利用概率或确定性地震危险性分析确定。强震作用下，大坝可能发生非弹性变形，因此需要在时域内进行地震分析。此外，地震对大坝造成的危害包括地面震动、断层移动、块体移动等。工程师所需的地面运动并非实际的地震地面运动，而是地面运动模型，用以进行大坝的抗震安全设计。同时必须牢记，在大坝较长的生命周期内，需要进行多次大坝安全评估。

关键词：大坝抗震设计地震安全性已建坝设计标准地震灾害可持续性使用寿命

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Seismic performance of moment resisting steel frame subjected to earthquake excitations

Fadzli M. NAZRI, Pang Yew KEN

《结构与土木工程前沿（英文）》 2014年第8卷第1期页码 19-25 doi: 10.1007/s11709-014-0240-3

摘要： This study presents static and dynamic assessments on the steel structures. Pushover analysis (POA) and incremental dynamic analysis (IDA) were run on moment resisting steel frames. The IDA study involves successive scaling and application of each accelerogram followed by assessment of the maximum response. Steel frames are subjected to nonlinear inelastic time history analysis for 14 different scaled ground motions, 7 near field and 7 far field. The results obtained from POA on the 3, 6 and 9 storey steel frames show consistent results for both uniform and triangular lateral loading. Uniform loading shows that the steel frames exhibits higher base shear than the triangular loading. The IDA results show that the far field ground motions has caused all steel frame design within the research to collapse while near field ground motion only caused some steel frames to collapse. The POA can be used to estimate the performance-based-seismic-design (PBSD) limit states of the steel frames with consistency while the IDA seems to be quite inconsistent. It is concluded that the POA can be consistently used to estimate the limit states of steel frames while limit state estimations from IDA requires carefully selected ground motions with considerations of important parameters.

关键词： incremental dynamic analysis (IDA) pushover analysis performance-based seismic design

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Genetic basis of adult-onset nephrotic syndrome and focal segmental glomerulosclerosis

null

《医学前沿（英文）》 2017年第11卷第3期页码 333-339 doi: 10.1007/s11684-017-0564-1

摘要：

Nephrotic syndrome (NS) is one of the most common glomerular diseases with signs of nephrosis, heavy proteinuria, hypoalbuminemia, and edema. Dysfunction of glomerular filtration barrier causes protein loss through the kidneys. Focal segmental glomerulosclerosis (FSGS) accounts for nearly 20% of NS among children and adults. Adult-onset FSGS/NS is often associated with low response to steroid treatment and immunosuppressive medication and poor renal survival. Several genes involved in NS and FSGS have been identified by linkage analysis and next-generation sequencing. Most of these genes encode proteins and are highly expressed in glomerular podocytes, which play crucial roles in slit-diaphragm signaling, regulation of actin cytoskeleton dynamics and maintenance of podocyte integrity, and cell–matrix interactions. In this review, we focus on the recently identified genes in the adult-onset NS and FSGS and discuss clinical significance of screening of these genes.

关键词： nephrotic syndrome focal segmental glomerulosclerosis genetic

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An old issue and a new challenge for nuclear reactor safety

F. D’AURIA

《能源前沿（英文）》 2021年第15卷第4期页码 854-859 doi: 10.1007/s11708-021-0729-0

摘要： Nuclear reactor safety (NRS) and the branch accident analysis (AA) constitute proven technologies: these are based on, among the other things, long lasting research and operational experience in the area of water cooled nuclear reactors (WCNR). Large break loss of coolant accident (LBLOCA) has been, so far, the orienting scenario within AA and a basis for the design of reactors. An incomplete vision for those technologies during the last few years is as follows: Progress in fundamentals was stagnant, namely in those countries where the WCNR were designed. Weaknesses became evident, noticeably in relation to nuclear fuel under high burn-up. Best estimate plus uncertainty (BEPU) techniques were perfected and available for application. Electronic and informatics systems were in extensive use and their impact in case of accident becomes more and more un-checked (however, quite irrelevant in case of LBLOCA). The time delay between technological discoveries and applications was becoming longer. The present paper deals with the LBLOCA that is inserted into the above context. Key conclusion is that regulations need suitable modification, rather than lowering the importance and the role of LBLOCA. Moreover, strengths of emergency core cooling system (ECCS) and containment need a tight link.

关键词： large break loss of coolant accident (LBLOCA) nuclear reactor safety (NRS) licensing perspectives basis for design of water cooled nuclear reactors (WCNR)

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汶川地震灾害地图集编制工程

陈军,史培军,王东华,赵勇,王静爱,刘连友,戴昌礼,曾文军

《中国工程科学》 2009年第11卷第8期页码 24-28

摘要：

《汶川地震灾害地图集》综合应用先进的地图与地理信息可视化方法,较为系统地描述与表达了汶川特大地震的孕灾环境、承灾体、致灾因子、灾情评估等，反映了从灾害发生、灾后救援、到灾后重建的有关过程，为政府应对巨灾、相关科学研究、灾后恢复重建、公灾科普教育等提供了翔实的参考依据与文献资料。介绍了该地图集设计和编制的总体思路、内容结构、表示方法以及工程组织实施方法。

关键词：汶川地震灾害地图集地理信息可视化编制工程

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Seismic design of high-rise towers for cable-stayed bridges under strong earthquakes

Yan XU, Shide HU

《结构与土木工程前沿（英文）》 2011年第5卷第4期页码 451-457 doi: 10.1007/s11709-011-0127-5

摘要： This paper presents the first of a series of studies on the seismic design of high-rise towers for cable-stayed bridges under strong earthquakes. One practical cable-stayed bridge with a 730 m long main span and two high-rise towers over 200 m in height was selected for this study. The preliminary results show that compared with piers, the tower is more vulnerable to pulse-like earthquakes, and it may develop plasticity at certain locations. In addition, viscous dampers may not have the same effect during pulse-like earthquakes as they do under site-specific earthquakes. Hence, reoptimization of damper parameters or reconsideration of other energy dissipation devices will be needed if strong earthquakes are likely to occur.

关键词： high-rise tower cable-stayed bridge strong earthquake seismic design

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西南涡大气科学试验的观测布局理论与实践

李跃清,徐祥德,赵兴炳

《中国工程科学》 2012年第14卷第9期页码 35-45

摘要：

我国是气象灾害十分严重的国家。西南涡是一个非常重要的灾害性天气系统，与我国夏半年的暴雨洪涝灾害密切相关，对国民经济、社会发展和人民生命财产安全都有着严重的影响。基于西南涡理论研究与科学试验现状，阐述了西南涡大气科学试验的观测基础对西南涡基本信息、理论研究和业务预报的重要意义。从站点分布、设备技术、观测要素等方面，提出了西南涡大气科学试验观测布局的设计思想与技术原则。在此基础上，系统设计了西南涡大气科学试验的观测布局工程，并于2010年、2011年开展了两次西南涡大气科学试验，检验了观测布局设计思想的正确性，推动了西南涡研究与业务的进展。最后，从西南涡大气科学试验的需求、现状和效果，进一步指出了加强其观测布局理论研究和具体实践，对我国经济发展、防灾减灾的重要意义。

关键词：西南涡科学试验观测基础布局技术

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Developing effective tumor vaccines: basis, challenges and perspectives

XU Qingwen, CHEN Weifeng

《医学前沿（英文）》 2007年第1卷第1期页码 11-19 doi: 10.1007/s11684-007-0003-9

摘要： A remarkable advance in tumor immunology during the last decade is the elucidation of the antigenic basis of tumor recognition and destruction. A variety of tumor antigens have been identified using several strategies including conventional experiments and newly developed bioinformatics. Among these antigens, cancer/testis antigen (CT antigen) is considered to be the most promising target for immunotherapy by vaccination. Successful immunotherapy of tumors requires understanding of the natural relationship between the immune system and tumor in the status of differentiation, invasion and maturation. Continued progress in development of effective cancer vaccines depends on the identification of appropriate target antigens, the establishment of optimal immunization strategies without harmful autoimmune responses and the ability of manipulating tumor microenvironment to circumvent immune suppression and to augment the anti-tumor immune response.

关键词： development conventional identification elucidation Successful immunotherapy

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Aseismic smart building isolation systems under multi-level earthquake excitations: Part I, conceptualdesign and nonlinear analysis

Min-Ho CHEY,J. Geoffrey CHASE,John B. MANDER,Athol J. CARR

《结构与土木工程前沿（英文）》 2015年第9卷第3期页码 286-296 doi: 10.1007/s11709-015-0307-9

摘要： As a novel structural control strategy, tuned mass damper (TMD) inspired passive and semi-active smart building isolation systems are suggested to reduce structural response and thus mitigate structural damage due to earthquake excitations. The isolated structure’s upper stories can be utilized as a large scaled TMD, and the isolation layer, as a core design point, between the separated upper and lower stories entails the insertion of rubber bearings and (i) viscous dampers (passive) or (ii) resettable devices (semi-active). The seismic performance of the suggested isolation systems are investigated for 12-story reinforced concrete moment resisting frames modeled as “10+ 2” stories and “8+ 4” stories. Passive viscous damper or semi-active resettable devices are parametrically evaluated through the optimal design principle of a large mass ratio TMD. Statistical performance metrics are presented for 30 earthquake records from the three suites of the SAC project. Based on nonlinear structural models, including P-delta effects and modified Takeda hysteresis, the inelastic time history analyses are conducted to compute the seismic performances across a wide range of seismic hazard intensities. Results show that semi-active smart building isolation systems can effectively manage seismic response for multi-degree-of freedom (MDOF) systems across a broader range of ground motions in comparison to uncontrolled case and passive solution.

关键词： tuned mass damper smart building isolation resettable device non-linear statistical assessment

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Leakage location system for oil pipeline on basis of stress wave detection

WANG Bangfeng, CHEN Renwen

《机械工程前沿（英文）》 2008年第3卷第3期页码 307-312 doi: 10.1007/s11465-008-0047-9

摘要： An online monitoring system was developed for rapidly determining the exact location of the holing position in an oil pipeline by monitoring and analyzing the characteristics of the strain wave caused by the hole. The system has a master-slaver computer structure based on a remote wireless network. The master system takes charge of managing and controlling the whole system, identifying the holing stress wave, and calculating the holing position. The slaver system is responsible for sampling the strain wave signal from the pipeline. The characteristics of the strain wave signal are extracted by a Hilbert-Huang transform based on a signal processing approach. The exact holing position can be obtained by a time delay locating method with stress wave characteristics. The experimental results of the in-service pipeline show that the average locating error of the system is less than 10 m, the accuracy ratio for the holing alarm is more than 90%, and the time that the system takes to respond to the leakage is less than 10 s.

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Experience gained in analyzing severe accidents for WWER RP using CC SOCRAT

《能源前沿（英文）》 2021年第15卷第4期页码 872-886 doi: 10.1007/s11708-021-0796-2

摘要： The current Russian regulatory documents on the safety of nuclear power plant (NPP) specify the requirements regarding design basis accidents (DBAs) and beyond design basis accidents (BDBAs), including severe accidents (SAs) with core meltdown, in NPP design (NP-001-15, NP-082-07, and others). For a rigorous calculational justification of BDBAs and SAs, it is necessary to develop an integral CC that will be in line with the requirements of regulatory documents on verification and certification (RD-03-33-2008, RD-03-34-2000) and will allow for determining the amount of data required to provide information within the scope stipulated by the requirements for the structure of the safety analysis report (SAR) (NP-006-16). The system of codes for realistic analysis of severe accidents (SOCRAT) (formerly, thermohydraulics (RATEG)/coupled physical and chemical processes (SVECHA)/behavior of core materials relocated into the reactor lower plenum (HEFEST)) was developed in Russia to analyze a wide range of SAs at NPP with water-cooled water-moderated power-generating reactor (WWER) at all stages of the accident. Enhancements to the code and broadening of its applicability are continually being pursued by the code developers (Nuclear Safety Institute of the Russian Academy of Sciences (IBRAE RAN)) with OKB Gidropress JSC and other organizations. Currently, the SOCRAT/1 code can be used as a base tool to obtain realistic estimates for all parameters important for computational justification of the reactor plant (RP) safety at the in-vessel stage of SAs with fuel melting. To perform analyses using CC SOCRAT/1, the experience gained during execution of thermohydraulic codes is applied, which allows for minimizing the uncertainties in the results at the early stage of an accident scenario. This study presents the results of the work performed in 2010–2020 in OKB Gidropress JSC using the CC SOCRAT/1. Approaches have been considered to develop calculational models and analyze SAs using CC SOCRAT. This process, which is clearly structured in OKB Gidropress JSC, provides a noticeable reduction in human involvement, and reduces the probability of erroneous results.

关键词： system of codes for realistic analysis of severe accidents (SOCRAT) design basis accidents (DBAs) severe accidents (SAs) computer code (CC) nuclear power plant (NPP) design water-cooled water-moderated (WWER) modeling model safety requirements